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In vitro/ex vivo analyses

In vitro/ex vivo analyses

•Permeation studies

•Mucoadhesion studies

•Stability studies

Formulation development

•Oral delivery systems

•Nasal delivery systems

•Buccal delivery systems

•Vaginal delivery systems

(Pre)clinical studies

In vitro/ex vivo analyses are the first steps to develop an optimised drug delivery system. Parameters including drug solubility, Log P / Log D, stability and membrane permeability are the basis for the first crucial strategic decisions to define the route of administration (e.g. oral versus subcutaneous injection) and the choice of delivery system. In addition, the first orientating bioavailability calculations will rely on these data.

→  Permeation studies

→  Mucoadhesion studies

→  Stability studies

 

 

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